Harriet Beecher Stowe's contributions significantly influenced public opinion on slavery, particularly through her seminal work "Uncle Tom's Cabin." This novel humanized enslaved individuals and exposed the brutal realities of slavery, igniting widespread empathy and outrage across the United States and beyond. Stowe’s portrayal of moral dilemmas and the impacts of slavery on families not only galvanized the abolitionist movement but also set a precedent for using literature as a tool for social change. Her activism and literary achievements left an indelible mark on American culture and advocated for human rights.