The artist known for the creation of the Mona Lisa is Leonardo da Vinci. Painted in the early 16th century, the Mona Lisa is renowned for its captivating subject and masterful use of sfumato. Da Vinci's innovative techniques and attention to detail have made this artwork a timeless representation of Renaissance art. The painting's enigma and da Vinci's prowess as an artist contribute to its enduring legacy and fascination worldwide.