Sacagawea faced numerous challenges during the Lewis and Clark Expedition, including navigating foreign terrain and potential conflicts with Native American tribes. As a Shoshone woman, she was a key interpreter and guide, using her cultural knowledge to ease tensions during encounters with other tribes. The harsh conditions of the wilderness presented further obstacles, such as severe weather and limited resources. Furthermore, her role as a mother—carrying her infant son along the journey—added to her struggles. Sacagawea’s resilience and adaptability were essential for the success of the expedition.