F. Scott Fitzgerald made notable contributions to American literature through his exploration of the American Dream and the disillusionment that followed it. His most famous work, "The Great Gatsby," critiques the excesses of the Jazz Age and the moral decay underlying societal glamour. Fitzgerald’s vivid characterizations and rich symbolism illuminate themes of wealth, love, and the pursuit of happiness, reflecting the complexities of American life in the 1920s. He employed a lyrical writing style, which captured the zeitgeist of his era and continues to resonate with readers today, solidifying his legacy as a literary giant.