Florence Nightingale made noteworthy contributions to public health through her pioneering work in nursing and healthcare reform. She established the principles of sanitation and hygiene in hospitals, which drastically reduced mortality rates during the Crimean War. Nightingale's approach included meticulous data collection and statistical analysis, leading to evidence-based nursing practices. She founded the first secular nursing school, the Nightingale School of Nursing, and her efforts laid the groundwork for modern nursing and hospital care. Nightingale's legacy endures today in the ongoing advocacy for health standards and welfare.