Paul Farmer encountered various obstacles in his global health initiatives. Working in impoverished regions like Haiti, he faced logistical challenges in providing adequate healthcare, particularly in resource-strapped settings. Despite resistance from systemic inequalities and bureaucratic hurdles, Farmer remained committed to his vision of accessible healthcare for all. His founding of Partners In Health exemplified a model of community-based care, integrating social justice into health practice. These struggles informed his approach to tackling health disparities and reinforcing the necessity of interdisciplinary collaboration in addressing global health inequalities.