Vincent van Gogh's personal struggles, particularly his battles with mental illness, profoundly informed his art. His turbulent life experiences, including feelings of isolation and despair, found expression in his vivid, emotive paintings. The struggles with his mental health led to an intense exploration of color and emotion, evident in works like The Starry Night. Van Gogh also faced rejection and poverty, which added layers of complexity to his artistic vision. Ultimately, these personal challenges fueled his creativity, allowing him to transform pain into profound artistic expression that resonates with audiences today.