Yayoi Kusama's artistic vision was driven by significant experiences, including her struggles with mental health and isolation. Overcoming traumas from her childhood in Japan, she often expressed her psychological landscape through her art, utilizing polka dots and infinity rooms to symbolize overwhelm and transcendence. Her time in the New York avant-garde scene further enriched her work, incorporating diverse influences like pop art and female empowerment. Ultimately, these experiences formed a unique artistic identity that connects deeply with audiences.