Maya Angelou's work is significant in the context of American literature due to her powerful exploration of race, identity, and resilience. Her autobiographical series, starting with "I Know Why the Caged Bird Sings," brought to light the struggles of African Americans, particularly women, and the societal challenges they faced. Angelou's poignant storytelling and lyrical prose resonate with themes of self-discovery and empowerment, making her work an essential part of the literary canon. Through her artistry, Angelou challenged stereotypes and inspired countless readers, advocating for social justice and equality in a racially divided America.