Edgar Allan Poe's works were influenced by several key factors including his personal tragedies, a fascination with the macabre, and the literary movements of his time. The death of loved ones, particularly his mother and wife, profoundly impacted his themes of loss and sorrow. Poe was also influenced by the Romantic movement, which emphasized emotion and individuality in literature, shaping his style and narratives. His experiences with mental illness and struggles with alcoholism further informed his depictions of madness and despair. Poe's unique blend of gothic elements and psychological depth made his contributions to literature significant and enduring.