The influential figure who led the campaign for reproductive rights in the U.S. is Margaret Sanger. As a passionate advocate for women's access to contraception and family planning, Sanger founded the American Birth Control League, which later became Planned Parenthood. Her activism in the early 20th century challenged societal norms and aimed to empower women to make choices about their reproductive health. Sanger’s efforts laid the groundwork for significant legal and cultural shifts regarding women's reproductive rights, making her a pivotal figure in the ongoing battle for gender equality and health.