The first African American woman to become a billionaire through cosmetics is Madam C.J. Walker. She built a successful beauty empire in the early 20th century, focusing on products for African American women. Walker's entrepreneurial spirit and marketing strategies revolutionized the beauty industry, providing jobs and economic empowerment in her community. Her legacy extends beyond her business achievements, as she became a philanthropist and activist for civil rights, representing an inspiring figure in American history.