The first female African American to become a physician in the U.S. was Rebecca Lee Crumpler. Earning her medical degree in 1864, she broke significant barriers in a male-dominated field and during a time when opportunities for women, especially women of color, were severely limited. Crumpler’s focus on treating women and children, particularly in underserved communities, underscored her dedication to improving health outcomes. Her pioneering journey exemplifies resilience and commitment to healthcare, laying the groundwork for future generations of female physicians.