Best practices that foster student engagement in large classrooms include differentiated instruction, interactive activities, and the use of technology. Educators can implement small group discussions, think-pair-share strategies, and real-time polls to encourage participation. Incorporating multimedia presentations and hands-on projects caters to various learning preferences and keeps students engaged. Establishing clear expectations and maintaining a positive classroom atmosphere also promote student involvement. By creating opportunities for meaningful interaction and feedback, instructors can enhance student engagement and facilitate a more effective learning experience in larger environments.