Strategies to tackle the challenges of the UPSC interview include thoroughly researching current affairs and understanding their implications. Candidates should practice mock interviews to build confidence and improve communication skills. Creating a comprehensive self-summary helps articulate personal strengths and experiences effectively. Additionally, developing an authentic understanding of personal opinions on various societal issues can lead to more engaging conversations with the interview panel. Finally, remaining calm and composed under pressure and maintaining a positive attitude can significantly enhance overall performance in the interview process.