People typically celebrate the Feast of San Gennaro in New York City with a vibrant street festival featuring Italian-American culture, food stalls, and religious processions. It highlights the Saint Gennaro, a patron saint of Naples, with a mass at a local church. The event includes live entertainment, performances by musicians, and the infamous cannoli, sausage and peppers, and other traditional dishes. The festival, taking place in Little Italy, usually spans over several days in September, attracting many visitors to partake in both religious and festive activities.