The organ responsible for detoxifying chemicals in the body is the liver. The liver is a vital organ located in the upper right abdomen and plays a crucial role in various metabolic processes, including detoxification, protein synthesis, and the production of biochemicals necessary for digestion. It filters blood coming from the digestive tract, removing toxins and processing nutrients. The liver also produces bile, which helps in fat digestion and absorption. Due to its numerous essential functions, the liver is critical to maintaining overall health, and any dysfunction can lead to serious health complications.