The ceiling of the Sistine Chapel was painted by Michelangelo Buonarroti. This masterpiece took four years to complete, beginning in 1508 and finishing in 1512. The frescoes depict biblical scenes, most notably The Creation of Adam, where God extends his hand to give life to Adam. Michelangelo's extraordinary talent for rendering human figures, capturing movement, and intricate details in his work made the Sistine Chapel a hallmark of Renaissance art and a significant cultural landmark.