The major US city located on the shores of Lake Michigan is Chicago. Known for its influential history, architecture, and cultural scene, Chicago is the third-largest city in the United States. The city features a vibrant downtown area, famous for its skyline, museums, and theaters. Popular attractions include the Art Institute, Millennium Park, and the Navy Pier. Chicago is also renowned for its diverse culinary offerings, including deep-dish pizza and hot dogs. The city's location on the lake makes it a significant port and a hub for trade and commerce.