Sitting for long periods can negatively affect health by increasing the risk of obesity, cardiovascular disease, and metabolic syndrome. Prolonged sedentary behavior can lead to poor posture, which may cause back and neck pain. Additionally, inactivity impacts muscle strength and endurance. To counteract these effects, it’s essential to incorporate regular breaks, light physical activity, or stretching throughout the day, promoting better overall health and well-being while reducing the risks associated with a sedentary lifestyle.