The effects of high-fructose corn syrup (HFCS) on health are primarily negative, as it is linked to increased obesity and metabolic disorders. HFCS is often found in many processed foods and sugary beverages, contributing to excessive calorie consumption without providing nutritional benefits. Regular intake can lead to insulin resistance, higher triglyceride levels, and increased fat accumulation in the liver. These factors collectively heighten the risk for conditions like type 2 diabetes and heart disease, underscoring the importance of moderating HFCS consumption for better health.