Key factors contributing to successful weight loss include maintaining a calorie deficit, adopting a balanced diet, and incorporating regular physical activity. A focus on whole, nutrient-dense foods over processed options promotes satiety and better nutrition. Moreover, setting realistic goals and tracking progress fosters accountability and motivation. Behavioral strategies, such as meal planning and mindful eating, can also enhance outcomes. Lastly, consistent support from friends, family, or weight loss groups can encourage adherence to lifestyle changes, ultimately leading to long-term results.