The feeling of ‘runner’s high’ is attributed to the release of endorphins and other neurotransmitters, such as dopamine and serotonin, during prolonged aerobic exercise. As physical activity elevates heart rate and circulation, these chemicals promote a sense of well-being and euphoria, often characterized by reduced perceptions of pain or fatigue. The phenomenon can motivate individuals to continue exercising, fostering a positive feedback loop between physical activity and emotional uplift. Understanding this connection underscores the psychological benefits of regular exercise and its role in enhancing mental health.