Metabolic adaptation refers to the body's physiological changes that occur in response to caloric restriction and weight loss. As individuals lose weight, their metabolic rate may decrease, making it more challenging to continue losing weight or maintain weight loss. This adaptation can be a result of decreased muscle mass, hormonal changes, and alterations in energy expenditure. Understanding metabolic adaptation is crucial for developing effective weight loss strategies that incorporate sustainable lifestyle changes to promote long-term success in weight management.