Muscle atrophy is the wasting or loss of muscle tissue, often caused by disuse, aging, or underlying medical conditions. Disuse can occur due to prolonged inactivity, such as during bed rest or immobilization, leading to a decrease in muscle strength and size. Aging naturally contributes to muscle loss, known as sarcopenia. Additionally, diseases like cancer, chronic obstructive pulmonary disease (COPD), or neurological disorders can trigger atrophy due to reduced physical activity and altered metabolic states. Addressing the underlying causes and engaging in consistent physical activity can help mitigate muscle atrophy.