High cholesterol can significantly impact heart health by increasing the risk of atherosclerosis, where plaque builds up in the arteries, leading to restricted blood flow. This condition can result in serious events such as heart attacks and strokes. High cholesterol levels can be attributed to diet, lifestyle, and genetics. Managing cholesterol through a balanced diet, exercise, and sometimes medication is essential to reduce these risks. Regular screening helps monitor cholesterol levels and allows for timely interventions that can improve heart health and overall longevity.