Hormones play a pivotal role in weight regulation by influencing appetite, metabolism, and fat distribution. Hormones like leptin and ghrelin are key players, with leptin signaling satiety and ghrelin stimulating hunger. An imbalance in these hormones can lead to overeating or inadequate energy expenditure. Additionally, insulin regulates blood sugar levels and fat storage, while cortisol, the stress hormone, can contribute to fat accumulation, particularly in the abdominal area. Understanding hormonal interactions can aid in developing effective weight management strategies and optimizing overall health.