The significance of the Battle of Gettysburg during the American Civil War, fought from July 1 to July 3, 1863, lies in its status as a turning point in the conflict. It marked the largest battle of the war and resulted in a critical defeat for the Confederate Army, led by General Robert E. Lee. This Union victory, under the command of General George Meade, halted Lee's invasion of the North and boosted Northern morale. Additionally, the battle's high casualties underscored the war's brutality, influencing public perception and shaping subsequent military strategies, ultimately contributing to the Union's eventual victory.