The significance of the Preamble in the U.S. Constitution lies in its articulation of foundational principles and the purpose of the document. It serves as an introduction that outlines the fundamental ideas guiding the formation of the government, including promoting justice, ensuring domestic tranquility, providing for the common defense, promoting the general welfare, and securing the blessings of liberty. The Preamble engenders a sense of unity and purpose, reflecting the aspirations of the framers to create a representative government that serves its citizens. It has also been cited in numerous legal and political discussions regarding the interpretation of constitutional rights and roles.