The U.S. involvement in World War I significantly influenced subsequent events by establishing America as a global power. The war catalyzed social and political changes domestically, including the acceleration of the women's suffrage movement and shifts in labor dynamics. Internationally, the U.S. played a crucial role in shaping the post-war landscape, contributing to the formation of the League of Nations, although the Senate rejected U.S. membership. The Treaty of Versailles set the stage for future conflicts, and America's withdrawal into isolationism during the interwar period laid the groundwork for the rise of totalitarian regimes and ultimately World War II.