The ancient city that served as the center of the Minoan civilization and is known for its palace at Knossos is **Crete**. This civilization, which flourished from approximately 2600 to 1100 B.C., is noted for its advanced architecture, art, and trade networks. The Palace of Knossos features elaborate designs, multi-story buildings, and intricate frescoes depicting various aspects of Minoan life. Excavations of the site have provided valuable insights into early European civilization and the complex societal structures that existed prior to the rise of classical Greek culture.