The Reformation in England was primarily led by King Henry VIII. His break from the Catholic Church in the 16th century was driven by personal and political motives, including his desire for an annulment of his marriage to Catherine of Aragon, which the Pope refused to grant. In 1534, Henry established the Church of England, asserting his authority over religious matters and eliminating papal influence in English affairs. This act initiated a series of religious reforms and conflicts, marking a significant shift in English religious and political landscapes, ultimately shaping the future of England and its relationship with Roman Catholicism.