The significance of the 1964 Civil Rights Act lies in its comprehensive approach to ending discrimination based on race, color, religion, sex, or national origin. This landmark legislation marked a critical turning point in the American civil rights movement, outlawing segregation in schools, workplaces, and public accommodations. It established the Equal Employment Opportunity Commission (EEOC) to enforce anti-discrimination laws and promote equality in the workplace. The Act was pivotal in advancing social justice and civil rights, laying the foundation for subsequent legislation aimed at ensuring equal rights for all.